DMSO – Properties And Uses

Filed under: Uncategorized - 18 Oct 2012  | Spread the word !

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DMSO or Dimethyl sulfoxide is a by-product of the wood industry and also a commercial solvent. DMSO was used also as a pharmaceutical since 1961, when Dr. Jacob investigated its potential as a preservative. Soon, he discovered that this colourless liquid penetrated the skin very fast, but without damaging it.

This raised his curiosity and he started to study DMSO more intensely. He discovered that DMSO could be used as a pharmaceutical. Nonetheless, the FDA outlawed DMSO because it was a solvent and they didn’t know how it can be a medicine and also a substance that cleans engine parts. Additionally, studies showed that dogs injected with DMSO became blind. Later, it was discovered that this substance  causes blindness only in dogs. 


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Dr. Jacob believed that the FDA tried to kill interest and enthusiasm related to this chemical. Even if during 20 years of human and laboratory studies no one died, the FDA refused several applications to conduct clinical studies. It approved a single one for interstitial cystitis, which was approved for prescriptive use in 1978.

DMSO Properties And Uses

DMSO has several properties:

1. Penetrates the skin. This is an ability that was studied by many scientists. Even low concentrations are enough to cross membranes.

2. Carries other drugs across membranes. This makes it ideal for transporting morphine, sulfate, steroids, cortisone, insulin and other substances. This makes DMSO a great delivery system that prevents infection when skin is penetrated.

3. Is a topical analgesic. This property was proved by laboratory studies that show how DMSO reduces and cuts pain by blocking peripheral nerve. It also treats burns, sprains and cuts. Due to this property, it was used by many athletes. Nonetheless, its effects vanish when administration ceases.


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4. Reduces inflammation because it’s an antioxidant, stabilises membranes and is also a scavenger. DMSO treats all inflammatory conditions that aren’t caused by tumor or infection when patients don’t respond to conventional treatment. This substance is a great treatment for rheumatoid arthritis and it was the first non-steroidal anti-inflammatory substance discovered since aspirin.

5. Treats scleroderma, which is a disabling and rare, sometimes fatal disease caused by abnormal levels of collagen in the body. Studies showed that DMSO led to a wonderful improvement such as relief from stiffness, pain, an increase in strength and healing ischemic ulcers on fingertips.

6. Lowers intracranial pressure very fast and more effectively than other drugs. It also stabilized respiration, blood pressure, increased urine output by five times and blood flow. Doctors claim that is also a good product for stroke.


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Other Applications For DMSO

  • DMSO has great properties related to cancer. In several studies it was discovered that protects noncancer cells, delays the spread of cancer and enhances the chemotherapeutic agents.
  • It seems that it can destroy the resistance developed by certain bacteria.
  • DMSO can also prevent paralysis by keeping away the blood from reaching muscle that usually leads to the death of muscle tissue.
  • Due to its antioxidant effects, DMSO can also be a wonderful anti-aging product, but further research is necessary.


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It seems that DMSO is a great treatment for septicemia, toxic shock and radiation sickness, as well. We still don’t know if DMSO should be called a drug or a new therapeutic principle as long as there is still controversy over its clinical effectiveness. Nevertheless, a full investigation of its capabilities would be great because useful things could be discovered.

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DMSO – The History Of The Controverse

Filed under: Uncategorized - 10 May 2012  | Spread the word !

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DMSO is a substance named dimethylsulfoxide. Dr. Jacobs of the Oregon Health Sciences University was the one that needed a liquid in which to preserve the organs during a transplant. As he reached for a bottle of colorless substance, he discovered DMSO. In 1961, he was the first that discovered the huge potential of DMSO. This could penetrate the skin really quick and deep, without provoking damages. From that point, the life of Dr. Jacobs changed, as he dedicated it to learn more about the incredible substance called DMSO. The press heard the news and the pharmaceutical companies started selling DMSO. Moreover, the patients could use it and dose it alone, on their own like. This was a real problem for Dr. Jacobs, as he did not have time to test it, not had the FDA time enough for controlled and safe experimentation.

Even if the DMSO appears to have all the qualities that Dr. Jacobs claims that it has, in present, this substance is still not on the market. And why is that? After the DMSO was prohibited and the experiments finally began, a side effect of the substance was soon discovered. After the DMSO is gave to the patient through the skin, an annoying smell emanates from its mouth. It is very similar to that of garlic and even of the substance is used through the skin, the unpleasant smell still appears. To make sure the studies are true and the commercialization of the DMSO is not stopped from false reasons, they were done once again.

Neither the doctors, nor the patients knew who was receiving real DMSO and who was receiving placebo, but it only took a matter of minutes to discover who and what took. This smell creates a lot of problems and it is one of the main factors that prevent making the DMSO legal for all the doctors and patients that need it in treatments. Even if the DMSO is highly beneficial, companies do not want to put it on sale until this problem is solved, fearing that this will stop customers to buy it.

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DMSO and Interstitial Cystitis

Filed under: Uncategorized - 10 Apr 2012  | Spread the word !

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Interstitial cystitis, also known as bladder pain syndrome, is a chronic disease of the urinary bladder. Despite researchers having thought that this disease only affected menopausal women, they have now reached the conclusion that men and women of all ages can develop interstitial cystitis. However, its cause remains uncertain, as doctors did not manage to figure out yet what triggers this disease. Its symptoms are very painful, so interstitial cystitis can seriously affect the quality of life. The symptoms of interstitial cystitis include pain associated with the bladder, pain associated with urination, urinary frequency and urgency, and pressure in the bladder and/or pelvis.

Harvard researchers have compared interstitial cystitis to other diseases such as chronic kidney failure or cancer, which is why it is officially recognized as a disability. The good news is that the pain can be relieved, as there are several treatment approaches which can be used in this respect. DMSO is definitely one of the best ways to treat interstitial cystitis. DMSO stands for dimethyl sulfoxide and it is an organosulfur compound. The history of DMSO goes back to the 1960s, when Dr. Stanlet Jacob began to study the medicinal properties of this substance. Although the history of DMSO is very controversial, this substance is now the only medical approved drug for the treatment of interstitial cystitis. While this bladder instillation is the only one approved, it is unfortunately not that used in urology clinics.

Regarding interstitial cystitis, a 50% solution of DMSO is instilled into the bladder by means of a catheter. It is left there for about 15 minutes and then it puts the patient at ease. Since a 50% solution of DMSO is at risk of creating irreversible muscle contraction, a 25% solution is more recommended. Nevertheless, the long term use of DMSO is still controversial, given the fact that no one fully understands yet the method of action of this substance. Besides treating interstitial cystitis, DMSO has other medicine applications, too. Many people believe that DMSO is a great alternative treatment for cancer. However, this thesis has not been scientifically proved, either.

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DMSO Applications

Filed under: Uncategorized - 15 Mar 2012  | Spread the word !

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DMSO is the short name for Dimethyl sulfoxide, an organosulfur compound bearing the chemical formula (CH3)2SO. DMSO is a polar aprotic solvent that dissolves polar and nonpolar compounds. DMSO can be mixed with a large array of organic solvents, including water. DMSO is colorless and has the property of penetrating the skin easily. The substance was first synthesized by Alexander Zaytzev in 1866, but he only made a report about what he found out a year later. DMSO is produced on a large scale by the oxidation of dimethyl sulfide with nitrogen dioxide or oxygen. The substance has several applications – as a solvent, for reactions, in biology, medicine and veterinary medicine.

DMSO is used as a solvent because it is less toxic than other of its class. It is frequently used in Finkelstein reactions and in nucleophilic substitutions which involve salt. It has a high boiling point – at 372.2 degrees Fahrenheit and also a high freezing point, at 65.3 degrees Fahrenheit, which make it a great solvent. It dissolves a large range of analyzes and is perfect for many NMR spectroscopic studies. DMSO is also very used in the production of microelectronic devices.  The reactions of DMSO are useful for the deprotonation of ketones. Following this reaction, sodium enolates are formed. Through a similar process, DMSO helps phosphonium salts to form Wittig reagents and formamidium salts, diaminocarbenes.

In biology, DMSO is used in PCR and it is added to the mix before the reaction, to minimize the interfering reactions. DMSO is also a cryoprotectant and prevents cell death in the freezing process. Thanks to DMSO, cells can be stored safely in liquid nitrogen. DMSO is used in medicine since the 1960s, when a research team in Oregon discovered that the substance can penetrate the skins without producing damage, carrying other substances into the system. It is also used as an analgesic and as an antioxidant. Even so, the most common used of DMSO in medicine is as a drug delivery system. In veterinary medicine, this substance is used alone or combined with other to carry other substances through the skin. It is mostly used on horses.

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What Is DMSO

Filed under: Uncategorized - 09 Feb 2012  | Spread the word !

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DMSO has been the subject of a lot of controversies during the last years, but, unfortunately, a lot of people talking about it do not really know what DMSO is. DMSO is acronym meaning dimethylsulfoxide. This substance is a chemical that can cause a minor irritation of the skin. DMSO is made from wood pulp. It can penetrate the skin and studies have showed that it can also ease the healing of inflammation. DMSO can be used in many treatments, but until now, it cannot be used in most of them. Not many DMSO applications have approval and many pharmaceutical companies still wait to reach an agreement with U.S. Food and Drug Administration to gain it. In present, monumental research is done in support of DMSO, but because of its prohibition in America, many American citizens cross the borders to benefit of treatments including this substance.

Medical communities are fighting to obtain the approval to use DMSO at least in treating cystitis – the inflammation of the bladder wall, arthritis and bursitis. Although the veterinary use is approved for DMSO for decades, the human use is not. DMSO is used by veterinaries to cure dermatological disorders and tissue damage. Also in immunological therapies of animals, DMSO is successfully used in the United States. FDA has serious reasons not to grant the approvals of DMSO yet on humans, as the medical community still has to answer a few important questions regarding the use of this substances in treatments and cures.

In some countries, DMSO is already used. For the treatment of arthrosis, bursitis, muscular pain, interstitial cystitis, tissue necrosis and tissue damage, DMSO is an important substance. Not just for these problems is used, but DMSO also works as a vehicle to deliver in one’s blood other drugs to help other areas of the body of the patient. Although it is not an official news, it seems that athletes that suffer from bruises, pain and swelling use DMSO successfully. To prove the efficiency of this substance, decades of research have been made. Even so, FDA still refuses to give its approval for the medical use on humans.

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The DMSO Substance And Drugs

Filed under: Uncategorized - 16 Jan 2012  | Spread the word !

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The DMSO substance is a very powerful compound, that appears in numerous drugs and pharmaceuticals. Although in recent years DMSO has been the subject of many controversies, the substance’s alleged benefits make it be widely used in many fields. There are many products on the market nowadays that rely on the DMSO effects. They are usually drugs that treat inflammations and pain, as well as anti-aging creams. DMSO has several characteristics that have effects on the reduction of swellings and the relief of pain symptoms. In addition to this, the substance softens collagen, thus being a great addition to wrinkle cremes. In the past few years, the DMSO substance has been tested in connection to the treatment of cancer, which has lead to the surfacing of several issues and side-effects created by this compound.

The most frequent uses of drugs based on DMSO are related to inflammations. The effects produced by this substance lead to the decompression of the harmed tissue and to a rapid recovery of it. In addition to this, the substance may also be found in antioxidant compounds. The benefits of using such substances or drugs are related to an easy recovery process. The substance’s active components are assimilated by the organism and cause immediate reactions from the traumatized area. You will be happy to know that, through the usage of DMSO drugs, you will be able to recover fast from all inflammation and pain related health occurrences. 

The DMSO is a very powerful compound and there are numerous advertisements on how to properly use drugs based on it, in order to keep away from unwanted side-effects. The medical field uses this substance in many variants, but the DMSO can also be used for other reasons as well. You should not be surprised if you find that there are several drugs in veterinarian medicine that contain DMSO. Moreover, the Dimethyl Sulfoxide is actually a solvent, used in salt based chemical reactions. Due to its highly diversified uses, this product should be considered very carefully before any action.

 

 

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DMSO and Arthritis

Filed under: Uncategorized - 22 Dec 2011  | Spread the word !

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Over the years, DMSO has raised many concerns and controversies, as there are many debates on the topic. This is because DMSO, which stands for dimethyl sulfoxide, is believed to have an important part in treating cancer, and several other diseases. However, since the discovery of DMSO, in 1961, when the history of DMSO began, many things have changed, and many improvements have been brought to this industrial solvent. So here is some information regarding the possible links between DMSO and arthritis, to see if this substance can actually help people suffering from this condition.

Well, DMSO has many great properties: it relieves pain, it softens collagen and it also has anti-inflammatory characteristics. Besides the fact that it relieves pain and inflammation, DMSO is also thought to improve joint mobility in osteoarthritis, rheumatoid arthritis and scleroderma, because it increases blood flow to skin. These properties have thus linked DMSO to the treatment of arthritis. However, the use of DMSO is very controversial. The FDA has not approved its use in the course of treatment for arthritis, on the contrary, it has even shut down two clinical trials conducted on the subject. Moreover, some doctors, like Robert Bennett, from the Oregon Health Sciences University, claims that there are other drugs that work even better than DMSO, regarding arthritis.

On the other side, there are other doctors that point out to the use of DMSO in veterinary medicine. Some say that DMSO is a very common substance which is given by veterinarians as treatment, and that you will hardly find an animal which has not been treated with it. They also say that DMSO works just fine. What about the use of DMSO for humans, though? As I said, scientists have not concluded yet, as there are still many tests and trials that need to be made. The side effects of DMSO are still concerning, as they include dizziness, nausea, vomiting, headaches, constipation, diarrhea, or even anorexia. Skin irritation and dermatitis are also common, and if you suffer from other conditions, you should better stay away from DMSO. Nevertheless, if it turns out that DMSO can treat arthritis and other conditions, this product will revolutionize the pharmaceutical industry.

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DMSO Safety Matters

Filed under: Uncategorized - 14 Nov 2011  | Spread the word !

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DMSO stands for Dimethyl sulfoxide, and it was synthesised for the first time in 1866, by Alexander Zaytsev, a Russian scientist. DMSO is a natural substance, derived from wood pulp, and it is mostly used as a solvent. In the United States, DMSO has been used for more than 100 years now, but even though this substance can be very useful, people do not know how to handle it properly, so many accidents occur. It is thus important to learn about the safety measures that you need to take when handling DMSO, so you will avoid getting harmed.

First, you must remember that when working with DMSO, you must wear gloves at all times. There are some debates going on about the DMSO advisable gloves, because not all kinds of gloves are suited. While some people believe that thick rubber gloves are the most recommended, the truth is that surgical gloves are the only ones who offer an adequate protection, because they do not allow the DMSO to penetrate through them and attack your skin. Then, one of the most important safety warnings about DMSO is that pregnant women or women who may become pregnant should not use it. Women who are nursing should not handle DMSO, either. Another safety matter regarding DMSO is that under no circumstances you should let in come in contact with your eyes, nor any type of clothing or any other thing that may later come in contact with your skin.

It is very important to take these DMSO safety matters seriously, because while this substance can be very useful, it can also be extremely dangerous. One of the most unfortunate cases is the story of a technician who was working with the scientists that discovered DMSO. He used regular lab gloves when handling DMSO, and he almost died, because DMSO can cause severe damage to skin cells. You can see thus that DMSO is not something you can play with, so if you purchased this substance, make sure that you keep it in a safe, hidden place, and you take all the protection measures that you can when using it.

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DMSO Is Very Controversial

Filed under: Uncategorized - 10 Oct 2011  | Spread the word !

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DMSO comes from dimethyl sulfoxide. DMSO is a substance used since 1963. It was often believed that DMSO is toxic, but has important roles in medicine, though. DMSO works as an analgesic, antioxidant and anti-inflammatory. DMSO is very easy absorbed by the skin and body and makes no damages to it as other substances. Bursitis and arthritis, as well as herpes, are one of the health issues that can be solved with the help of DMSO. DMSO is still controversial, but we cannot deny its useful effect though.

To treat our health issues we can use DMSO gel or DMSO cream. DMSO gel is faster absorbed by our skin and gives us a colling effect. DMSO became even more controversial when a woman died and also when some studies proved that can damage the brain very badly. So, in some countries, DMSO is banned. One of its side effects can be itching or bleeding, so people should take care when they take DMSO. Their doctor should tell them by the potential dangers that DMSO implies. Our bodies are not the same, so we do not know how we will react. This is why we have to care care and to think twice if it is safe to use DMSO or not. It is very interesting that even though DMSO is controversial, it has good effects on brain activity or brain damage. This substance became very popular during the 60′s, but when strange things were discovered about it, it was legally controlled.

DMSO is extracted from some trees and it can also restore the damaged tissues as that of burnt people. It was also used to stop infection, so it has multiple uses, but this does not mean that is not dangerous at all. For some people has positive effects, while for others can be very dangerous. People should be more informed about the potential side-effects of many substances from pills, creams or gel they use for a lot of health problems. It is an important thing for our health, so we should ask the doctor if it is safe for us to take a certain pill.

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Facts About DMSO Side Effects

Filed under: Uncategorized - 07 Sep 2011  | Spread the word !

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DMSO is the short word for dimethyl sulfoxide. Although DMSO has been many times described as being toxic, its use in medicine is quite a common one. DMSO has been used in medicine since the 1963s. Nowadays, DMSO is being used as an analgesic, anti-inflammatory and antioxidant substance. DMSO is known to have very good effects when it comes to skin related conditions. Brain damage is also treated with the use of DMSO based treatments, as it can help patients restore brain activity and overcome their problems.

Sill, the most important fact about DMSO is that the substance can be used for medical purposes without damaging skin in any way and it can be extremely easy to absorb. This is the main aspect that makes DMSO largely used in medicine. DMSO is also a very efficient treatment to be recommended for inflammatory conditions. DMSO based creams are in fact very popular from this point of view. They can be used on the skin with low risks of damaging it. The use DMSO cream is most of the times recommended when talking about herpes and also to heal bursitis and arthritis. DMSO may also be recommended in treatment schemes for muscular pain, tissue damage or intestinal cystitis. Anyway, DMSO cream is many times considered to be the most efficient treatment when it comes to curing the herpes virus. And individuals who use DMSO based cream are experiencing the best results.

Anyway, there are some DMSO side effects you need to be aware of. Years ago a huge controversy was created when a woman died because of the use of DMSO. The woman was under treatment with DMSO when the death occurred and although no autopsy to show the exact cause of death was made, it has been believed that DMSO use was the one to blame. DMSO side effects include numerous risks. This is the main reason why DMSO use is currently limited by law. Well, when it comes to the DMSO side effects, studies have shown that DMSO use can produce brain injury and brain degeneration. Irritation and itching at the skin level can also be included in the category of DMSO side effects. Excessive bleeding is another DMSO side effect.

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